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The Programmatic and Clinical Management of DR-TB Online course provides clinical officers, nurses, paramedical staff and other health workers with the knowledge and skills to effectively solve the most frequent challenges in the management of drug-resistant tuberculosis.

Learners receive a certificate at the end of the training if they validate the end of the training assessment.

Course content

Module 1: Epidemiology and diagnosis

  • 1. Tuberculosis: who is the pathogen and what is the global burden?
    • Introduction
    • Knowing the pathogen
    • Burden of DR-TB and major gaps in DR-TB control
    • Conclusion
  • 2. Natural history of TB and how resistance occurs
    • Natural history
    • Drug resistance: how it occurs and how it can be prevented
    • What is driving drug resistance
    • Conclusion
  • 3. Diagnostic tests
    • Introduction
    • Specimen collection and transportation
    • Diagnostic tests for TB and DR-TB
    • Conclusion
  • 4. Case finding strategies
    • Introduction
    • Case finding strategies
    • Contact tracing
    • Conclusion
  • 5. Delivering DR-TB care through person-centered approach
    • Introduction
    • Support Interventions
    • Treatment Delivery
    • Role of the nurse
    • Conclusion

Module 2: Clinical presentation and treatment

  • 1. Clinical and radiological manifestations of TB
    • Introduction
    • Clinical Presentation
    • Radiological Presentation
    • Conclusion
  • 2. DR-TB Treatment
    • Introduction
    • Medications used for DR-TB
    • DR-TB regimens
    • WHO recommendations for treatment of DR-TB
    • Conclusion
  • 3. Adverse Events Management
    • Introduction
    • Definitions
    • Monitoring
    • Adverse events clinical management
    • Conclusion
  • 4. DR-TB in specific populations - Part I
    • DR-TB in HIV co-infected
    • DR-TB and diabetes mellitus
    • DR-TB in children
    • DR-TB in pregnancy
  • 5. DR-TB in specific populations - Part II
    • DR-TB in children
    • DR-TB in pregnancy

This Module contains an optional activity:

  • Management of QT prolongation
  • Management of peripheral neuropathy
  • Management of hearing loss
  • Management of optic neuritis

Module 3: Infection control, reporting and case studies

  • 1. TB treatment outcomes and interpretation of data
    • Introduction
    • Outcome definition
    • Use of recorded data for decision making
    • Examples
    • Conclusion
  • 2. Infection control
    • Introduction
    • Importance of TB Infection control
    • Administrative control measures
    • Environmental control measures
    • Personal protection
    • Conclusion
  • 3. Case study - Part I
    • Case presentation 1-10
  • 4. Case study - Part 2
    • Case presentation 1-10

At the end of the training, participants will

  • Understand the basics of TB care and prevention.
  • Understand how drug-resistance develops, transmits and how it can be prevented.
  • Know how TB and DR-TB are diagnosed.
  • Know the basic elements of treatment of TB and DR-TB.
  • Know how to monitor and manage adverse events and when to refer to a physician.
  • Consider TB management in special cases: children, pregnant women, diabetes melitus and HIV co-morbidity.
  • Can apply the basics of recording and reporting and TB data use for decision making in TB care and prevention.

Clinical officers, nurses, M&E and health information officers, TB program staff not directly involved in DR-TB clinical management

Module 1: Epidemiology and diagnosis
Module 2: Clinical presentation and treatment
Module 2: Clinical presentation and treatment | Optional activity
Module 3: Infection control, reporting and case studies
Assessment and Evaluation

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